3-氨基-1，2，4-三唑

产品名称（Product Name）

3-氨基-1，2，4-三唑

产品编号 （Product NO）

HZA-1101

英文名称

3-Ami,2,4-triazole

CAS 编号 (CAS NO)

1022-79-3

密度 1.1380
熔点 149-156°C
溶解性 Soluble in water (280 g/l) at 20 °C, methanol, ethanol, chloroform, and ethyl acetate (slightly). Insoluble in ether, and acetone.
产品介绍 3-Ami,2,4-triazole is a small molecule irreversible inhibitor of catalase, an enzyme responsible for converting cellular H2O2 into H2O and O2. Impeding the natural clearance of H2O2 from the cell by catalase has proven useful in studies investigating free radical-mediated damage of cardiac tissue in ischemia. 3-Ami,2,4-triazole also shows inhibition of imidazoleglycerol-phosphate dehydratase (HIS3) activity, which interrupts the biosynthesis of histidines. When 3-Ami,2,4-triazole is diazotized, the resulting 3-Diazo-1,2,4-triazole is shown to react specifically with tryptophan at acidic pH, presenting a method for determining the tryptophan content of proteins.
别名 3-氨基-1,2,4-三氮唑;3-氨基-1,2,4-三氮杂茂;氨基三唑;杀草强;Aminotriazole;Amitrol;3-AmiH-1,2,4-triazole
应用 An irreversible catalase inhibitor

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